Round 21 Matches
| 02/08/2019 at 20:00 | NAC Breda - AZ | 0 - 3 [FT] |
| 02/09/2019 at 18:30 | Heracles Almelo - Ajax | 1 - 0 [FT] |
| 02/09/2019 at 18:30 | sc Heerenveen - PEC Zwolle | 1 - 1 [FT] |
| 02/09/2019 at 20:45 | Feyenoord - De Graafschap | 4 - 0 [FT] |
| 02/09/2019 at 20:45 | VVV-Venlo - Willem II | 2 - 1 [FT] |
| 02/10/2019 at 12:15 | Fortuna Sittard - Excelsior | 4 - 1 [FT] |
| 02/10/2019 at 14:30 | FC Emmen - ADO Den Haag | 3 - 2 [FT] |
| 02/10/2019 at 14:30 | FC Groningen - Vitesse | 2 - 1 [FT] |
| 02/10/2019 at 16:45 | FC Utrecht - PSV | 2 - 2 [FT] |
Willem II - Vitesse 1 - 3
| G | Timon Wellenreuther |  Eduardo | G |
| D | Freek Heerkens  | Danilho Doekhi | D |
| D | Thomas Meiszner | Alexander Buttner | D |
| D | Diego Palacios | Rasmus Thelander | D |
| D | Fernando Lewis | Vyacheslav Karavaev | D |
| D | Damil Dankerlui |  Martin Odegaard | M |
| M | Pol Llonch | Navarone Foor | M |
| M | Daniel Crowley |  Matus Bero | M |
| M | Vurnon Anita | Thulani Serero | M |
| S | Fran Sol  | Oussama Darfalou | S |
| S | Donis Avdijaj | Bryan Linssen | S |
| D | Jordens Peters  | Thomas Bruns | M |
| M | Aras Ozbiliz | Roy Beerens | S |
| S | Kristofer Kristinsson | Thomas Buitink | S |