Round 21 Matches
| 02/08/2019 at 20:00 | NAC Breda - AZ | 0 - 3 [FT] |
| 02/09/2019 at 18:30 | Heracles Almelo - Ajax | 1 - 0 [FT] |
| 02/09/2019 at 18:30 | sc Heerenveen - PEC Zwolle | 1 - 1 [FT] |
| 02/09/2019 at 20:45 | Feyenoord - De Graafschap | 4 - 0 [FT] |
| 02/09/2019 at 20:45 | VVV-Venlo - Willem II | 2 - 1 [FT] |
| 02/10/2019 at 12:15 | Fortuna Sittard - Excelsior | 4 - 1 [FT] |
| 02/10/2019 at 14:30 | FC Emmen - ADO Den Haag | 3 - 2 [FT] |
| 02/10/2019 at 14:30 | FC Groningen - Vitesse | 2 - 1 [FT] |
| 02/10/2019 at 16:45 | FC Utrecht - PSV | 2 - 2 [FT] |
sc Heerenveen - Ajax 0 - 4
| G | Warner Hahn | Andre Onana | G |
| D | Dave Bulthuis |  Daley Blind | D |
| D | Kik Pierie | Rasmus Kristensen | D |
| D | Sherel Floranus | Maximilian Wober | D |
| D | Daniel Hoegh  | Matthijs de Ligt | D |
| M | Michel Vlap  |  Lasse Schone | M |
| M | Yuki Kobayashi | Donny van de Beek | M |
| M | Morten Thorsby | Frenkie de Jong | M |
| M | Ben Rienstra | Hakim Ziyech | M |
| S | Arber Zeneli | Kasper Dolberg | S |
| S | Sam Lammers |  Dusan Tadic | S |
| M | Rodney Kongolo  | Zakaria Labyad | M |
| M | Pelle van Amersfoort | David Neres | S |
| S | Mitchell van Bergen | Klaas-Jan Huntelaar | S |